Utilisation of Chimeric Lyssaviruses to Assess Vaccine Protection against Highly Divergent Lyssaviruses
نویسندگان
چکیده
منابع مشابه
Utilisation of Chimeric Lyssaviruses to Assess Vaccine Protection against Highly Divergent Lyssaviruses
Lyssaviruses constitute a diverse range of viruses with the ability to cause fatal encephalitis known as rabies. Existing human rabies vaccines and post exposure prophylaxes (PEP) are based on inactivated preparations of, and neutralising antibody preparations directed against, classical rabies viruses, respectively. Whilst these prophylaxes are highly efficient at neutralising and preventing a...
متن کاملEvolution of European bat lyssaviruses.
Forty-seven European bat lyssaviruses (EBL) and two African insectivorous bat lyssaviruses (Duvenhage viruses) were selected for a comparison to be made of their evolutionary relationships. Studies were based on direct sequencing of the PCR-amplified products of the 400 nucleotides coding for the amino terminus of the nucleoprotein. Phylogenetic relationships were analysed after bootstrap resam...
متن کاملBat Lyssaviruses, Northern Vietnam
Technical Appendix Technical Appendix Table. Neutralization antibody titers against lyssaviruses in bats, by bat species and location, northern Vietnam* Location Bat species Neutralizing antibody titer † RABV DUVV EBLV-1 LBV Tuyen Quang Eonycteris spelaea 20 0 0 0 Eonycteris spelaea 0 0 20 0 Ia Io 20 0 0 0 Ia Io 0 20 0 0 Ia Io 0 20 0 0 Ia Io 10 0 20 0 Ia Io 10 10 40 0 Lang Son Taphozous cf. mel...
متن کاملEuropean Bat Lyssaviruses, the Netherlands
To study European bat lyssavirus (EBLV) in bat reservoirs in the Netherlands, native bats have been tested for rabies since 1984. For all collected bats, data including species, age, sex, and date and location found were recorded. A total of 1,219 serotine bats, Eptesicus serotinus, were tested, and 251 (21%) were positive for lyssavirus antigen. Five (4%) of 129 specimens from the pond bat, My...
متن کاملSurvey for Bat Lyssaviruses, Thailand
Surveillance for lyssaviruses was conducted among bat populations in 8 provinces in Thailand. In 2002 and 2003, a total of 932 bats of 11 species were captured and released after serum collection. Lyssavirus infection was determined by conducting virus neutralization assays on bat serum samples. Of collected samples, 538 were either hemolysed or insufficient in volume, which left 394 suitable f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Viruses
سال: 2018
ISSN: 1999-4915
DOI: 10.3390/v10030130